The core-inversible micelles for hydrophilic drug delivery.

نویسندگان

  • Wenzhe Huang
  • Changying Shi
  • Yu Shao
  • Kit S Lam
  • Juntao Luo
چکیده

A unique core-inversible micelle (CIM) was formed via PEG(5k)CA8 for hydrophilic drug delivery. An amyloid-fibril-inhibiting water-soluble molecule, congo red (CR), has been loaded into the hydrophilic core of CIMs. The targeting folate-CIMs significantly enhanced the intracellular delivery of hydrophilic CR in a folate receptor-expressing cell line.

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عنوان ژورنال:
  • Chemical communications

دوره 49 59  شماره 

صفحات  -

تاریخ انتشار 2013